On September 17, 2026, Cisco disclosed a critical zero-day vulnerability, CVE-2026-76460, in its Identity Services Engine (ISE) and ISE Passive Identity Connector (ISE-PIC) products. The flaw carries the maximum CVSS score of 10.0 and allows for a complete authentication bypass. Cisco's Product Security Incident Response Team (PSIRT) has confirmed active exploitation of this vulnerability in the wild, prompting an emergency patch release. Due to the severity and active exploitation, the U.S. Cybersecurity and Infrastructure Security Agency (CISA) has added it to its Known Exploited Vulnerabilities (KEV) catalog, requiring federal agencies to patch by September 19, 2026. Successful exploitation could grant an attacker root-level command execution, leading to a full system compromise.
The vulnerability, CVE-2026-76460, is an authentication bypass flaw stemming from insufficient authentication controls on a specific API endpoint within the ISE web-based management interface. An unauthenticated, remote attacker can exploit this by sending a specially crafted HTTP request to the vulnerable API. A successful request bypasses all authentication mechanisms, regardless of the device's configuration, granting the attacker unauthorized access. The ease of exploitation—requiring no authentication or user interaction—and the critical nature of ISE as a network access control gatekeeper contribute to its maximum severity rating.
The vulnerability affects multiple versions of Cisco's network access control solutions. Organizations using the following products should assume they are vulnerable and prioritize remediation:
Cisco has released software updates to address this vulnerability and strongly recommends all customers upgrade to a fixed release. There are no workarounds that can fully mitigate the flaw.
Cisco has confirmed that its PSIRT is aware of active, in-the-wild exploitation of CVE-2026-76460. The attackers' specific TTPs have not been fully disclosed, but the goal is to gain unauthorized access to the ISE management interface. Following a successful compromise, attackers could potentially achieve root command execution, allowing them to install backdoors, exfiltrate sensitive network information, or pivot to other parts of the network. The active exploitation led CISA to add the vulnerability to its KEV catalog on September 16, 2026, underscoring the immediate and significant risk to organizations.
A successful exploit of CVE-2026-76460 presents a catastrophic risk to an organization's security posture. As ISE is a central component for network authentication, authorization, and accounting (AAA), its compromise effectively dismantles network access controls. An attacker could:
Given that ISE often holds credentials and configurations for other network devices, its compromise can serve as a powerful launchpad for broader network intrusion.
Security teams may want to hunt for the following patterns which could indicate related activity:
Defenders should focus on both identifying vulnerable systems and detecting exploitation attempts.
401 Unauthorized or 200 OK responses to API endpoints that don't match legitimate administrative activity. This aligns with D3FEND's Network Traffic Analysis (D3-NTA).Patching is the only effective, long-term solution. However, some compensating controls can reduce risk.
New details on Cisco ISE zero-day (CVE-2026-76460) include specific detection commands and official advisory link for active exploitation.
Cisco has provided further details regarding the actively exploited ISE zero-day (CVE-2026-76460). The official Cisco Security Advisory link is now available, along with specific CLI commands for identifying potential compromise: 'show logging application ade/ADE.log | include "User with such username not found"'. This update also highlights the importance of monitoring for the log message 'User with such username not found' and suggests vulnerability scanning and file integrity monitoring as additional detection methods. The vulnerability remains critical with a CVSS score of 10.0.
CISA adds CVE-2026-76460 to its Known Exploited Vulnerabilities (KEV) catalog.
Cisco publicly discloses the vulnerability and releases emergency patches.
Deadline for U.S. Federal Civilian Executive Branch (FCEB) agencies to apply patches for CVE-2026-76460.

Cybersecurity professional with over 10 years of specialized experience in security operations, threat intelligence, incident response, and security automation. Expertise spans SOAR/XSOAR orchestration, threat intelligence platforms, SIEM/UEBA analytics, and building cyber fusion centers. Background includes technical enablement, solution architecture for enterprise and government clients, and implementing security automation workflows across IR, TIP, and SOC use cases.
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Every tactic, technique, and sub-technique used in this threat has been identified and mapped to the MITRE ATT&CK framework for consistent, actionable threat language.
Observables and indicators of compromise (IOCs) have been extracted and cataloged. Risk has been assessed and correlated with known threat actors and historical campaigns.
Detection rules, incident response steps, and D3FEND-aligned mitigation strategies are included so your team can act on this intelligence immediately.
Structured threat data is packaged as a STIX 2.1 bundle and can be visualized as an interactive graph — relationships between actors, malware, techniques, and indicators.
Sigma detection rules are derived from the threat techniques in this article and can be converted for deployment across any major SIEM or EDR platform.